Sulfonylureas are a class of commonly used oral hypoglycemic drugs, among which glimepiride is widely used in clinical practice due to its significant hypoglycemic effect and long-lasting effect. However, if these drugs are used illegally during food production, processing or storage or cause residues due to improper operation, they may pose a potential threat to consumer health. In order to quickly and accurately detect sulfonylurea drug residues in food, the Sulfonylurea (glimepiride) Colloidal Gold Rapid Detection Card came into being.
In simple terms, the Sulfonylurea (glimepiride) Colloidal Gold Rapid Detection Card is a rapid detection product based on colloidal gold immunochromatography technology. Its core principle is to use colloidal gold particles as tracer markers, and after binding to specific antibodies, qualitative or semi-quantitative detection of the target can be achieved through antigen-antibody immune reaction. During detection, the sample (such as meat, dairy products, grains, etc.) is dropwise into the detection card and sample hole, and the sample will move on the test strip through chromatography to react with the glimepiride-carrier protein conjugate coated in the detection line and the colloidal gold-labeled antibody of the quality control line. If there is glimepiride residue in the sample, it will compete with the conjugate of the detection line to bind the colloidal gold-labeled antibody, resulting in color development or no color development of the detection line, so as to quickly judge the result.
This type of detection card has significant advantages: first, it is fast, the entire detection process usually only takes 10-15 minutes, without waiting for long cultivation or complex reactions; second, it has high sensitivity, can reach the detection limit of ng level, and can accurately capture extremely small amounts of residues; third, it is easy to operate, without professional equipment and complex operations, and can be used by ordinary personnel after simple training; fourth, it is low cost. Compared with traditional instrument detection, the detection card has lower cost and is suitable for large-scale screening and on-site rapid detection.
In application scenarios, sulfonylurea (glimepiride) colloidal gold rapid detection cards are widely used in food production enterprises for raw material acceptance, processing process monitoring, on-site sampling inspection by market supervision departments, and rapid screening of imported and exported food. It can help regulators and enterprises find the problem of sulfonylurea drug residues in food in time, avoid substandard products from entering the market, and ensure the "safety on the tip of the tongue" of consumers.
In short, sulfonylurea (glimepiride) colloidal gold rapid detection card With its fast, sensitive and convenient characteristics, it has become an important tool for the detection of sulfonylurea drug residues in food, and plays an irreplaceable role in food safety supervision and quality control.