In today's increasingly concerned about the safety of cosmetics, sulfonamides, as a common antibacterial preservative, may cause irritation, allergies and even potential health risks to human skin if they are added illegally or residues exceed the standard in cosmetics. At this time, the rapid detection card for sulfonamides in cosmetics has become an important tool to protect product safety.
So, what exactly is this detection card? It is a rapid detection product based on colloidal gold immunochromatography technology, which is mainly used for qualitative or semi-quantitative screening of sulfonamide residues in cosmetics. The core principle is to use colloidal gold-labeled sulfonamide antibodies to bind specifically to sulfonamide antigens that may exist in the sample, and quickly determine whether there is a target substance by observing the color development results on the test strip.
For specific use, usually only the treated cosmetic samples (such as lotions, creams, lipsticks, etc.) are added dropwise to the sample hole of the test card, and the sample will flow along the chromatographic material on the test strip. If the sample contains sulfonamides, the antigen will bind to the colloidal gold-labeled antibody to form a complex. When it continues to move to the detection line (T-line), if the antigen concentration in the sample reaches a certain threshold, the complex will gather at the T-line, causing the T-line to develop color; if there is no antigen in the sample or the concentration is insufficient, the T-line will not develop color. At the same time, the quality control line (C-line) will always develop color, serving as an effective control for the detection response.
The advantages of this detection card are very significant. The first is fast, the entire detection process usually only takes 10-15 minutes, no need for complex instruments, ordinary operators can master with simple training; secondly, it has high sensitivity and can detect lower concentrations of sulfonamide drug residues; secondly, it is easy to operate, without the need for a professional laboratory environment, and can quickly complete the screening in the field or laboratory; in addition, the cost is relatively low, suitable for batch sample testing, which can effectively reduce the cost of detection.
At present, the test card is widely used in all kinds of cosmetics, including skin care products, makeup, washing products, etc., which can help enterprises quickly check product quality risks, and also provide efficient on-site law enforcement or sampling tools for regulatory authorities. By promptly discovering the illegal addition or residue of sulfonamides, it is an indispensable part of the cosmetic safety prevention and control system to ensure the safety of consumers from the source.